CRCST Practice Test
Updated October 27, 2026
The CRCST exam has 150 multiple-choice questions, 125 scored and 25 unscored, with a 3-hour limit. The scored questions follow HSPA’s content outline, with Cleaning, Decontamination and Disinfection, Preparation and Packaging, and the Sterilization Process making up about two-thirds of the exam. The free questions below mix the main areas. Each shows the answer and why.
For more depth, see decontamination, sterilization methods, sterilization monitoring and the CRCST exam guide.
Free CRCST practice questions
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(Decontamination) What is the most important step in reprocessing an instrument?Answer: AAn item that isn't clean can't be reliably disinfected or sterilized, because soil can protect microorganisms.
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(Spaulding) A flexible endoscope that touches mucous membranes needs at least:Answer: CSemi-critical items, which contact mucous membranes, need at least high-level disinfection under the Spaulding classification.
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(Sterilization) What does a Bowie-Dick test check?Answer: AThe Bowie-Dick test checks that air is removed properly in prevacuum steam sterilizers, typically each day before the first load.
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(Packaging) Why are instruments with ratchets left unlocked during sterilization?Answer: BOpen ratchets and hinges allow the sterilant to contact all surfaces of the instrument.
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(Storage) What happens to a sterile package that gets wet?Answer: CMoisture can carry microorganisms through the packaging, so wet packages are considered contaminated.
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(Sterilization) Which low-temperature method requires aeration to remove toxic residue?Answer: DEthylene oxide is toxic and absorbed by materials, so items must be aerated before use.
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(Department) What PPE is worn in the decontamination area?Answer: BDecontamination involves contact with blood, body fluids and splashes, so full PPE is worn.
Pass the CRCST exam on your first try
- All 207 questions on decontamination, disinfection, instruments, packaging, sterilization, storage, patient care equipment and professional skills
- An explanation for every answer, with the AAMI standard, CDC guideline or OSHA rule behind it
- Unlimited full 125-question practice exams, with each domain in its real share